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JCAD » 03-2010 (March 2010)

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Pregnancy is Not Detrimental to the Melanoma Patient with Clinically Localized Disease

March 2010

Mary S. Brady, MD; Memorial Sloan-Kettering Cancer Center, New York, New York; Nikki S. Noce, New York University Medical Center, New York, New York

Disclosure: The authors report no relevant conflicts of interest. Read the rest of this article »

Posted in 03-2010 (March 2010), Literature Review, Melanoma | No Comments »

The Use of a Contact Cooling Device to Reduce Pain and Ecchymosis Associated With Dermal Filler Injections

March 2010

Mark S. Nestor, MD, PhD, Center for Clinical and Cosmetic Research, Aventura, Florida; Glynis R. Ablon, MD, Ablon Skin Institute, Manhattan Beach, California; Mark A. Stillman, PhD, Center for Clinical and Cosmetic Research, Aventura, Florida

Disclosure: Dr. Nestor has received research grant support from and is a consultant and speaker for Medicis. Dr. Ablon has been a consultant for Medicis. Dr. Stillman reports no relevant conflicts of interest. This study was funded by an unrestricted educational grant from ThermoTek. The product used in this study was supplied by Medicis Aesthetics Incorporated. Read the rest of this article »

Posted in 03-2010 (March 2010), Dermal Fillers, Original Research | No Comments »

Topical Botulinum Toxin

March 2010

Ashley Collins, MD; Department of Biochemistry, North Carolina State University; Adnan Nasir, MD, Department of Dermatology, University of North Carolina, Chapel Hill, North Carolina

Abstract
Nanotechnology is a rapidly growing discipline that capitalizes on the unique properties of matter engineered on the nanoscale. Vehicles incorporating nanotechnology have led to great strides in drug delivery, allowing for increased active ingredient stability, bioavailability, and site-specific targeting. Botulinum toxin has historically been used for the correction of neurological and neuromuscular disorders, such as torticollis, blepharospasm, and strabismus. Recent dermatological indications have been for the management of axillary hyperhydrosis and facial rhytides. Traditional methods of botulinum toxin delivery have been needle-based. These have been associated with increased pain and cost. Newer methods of botulinum toxin formulation have yielded topical preparations that are bioactive in small pilot clinical studies. While there are some risks associated with topical delivery, the refinement and standardization of delivery systems and techniques for the topical administration of botulinum toxin using nanotechnology is anticipated in the near future.  (J Clin Aesthetic Dermatol. 2010;3(3):35–39.) Read the rest of this article »

Posted in 03-2010 (March 2010), Botulinum Toxin, Literature Review | No Comments »

5-Aminolevulinic Acid-based Photodynamic Intense Pulsed Light Therapy Shows Better Effects in the Treatment of Skin Photoaging in Asian Skin: A Prospective, Single-blinded, Controlled Trial

March 2010

Gao Yang, MD, Laser Center, Jinshan Hospital, Fudan University, Shanghai, China; Leihong Flora Xiang, MD, PhD Department of Dermatology, Huashan Hospital, Fudan University, Shanghai, China; Michael H. Gold, MD, Gold Skin Care Center, Tennessee Clinical Research Center, Nashville, Tennesee; Vanderbilt University School of Medicine, Department of Dermatology; Vanderbilt University School of Medicine, School of Nursing, Nashville, Tennesee; Huashan Hospital, Fudan University, Shanghai, China; Number One Hospital, China Medical University, Shenyang, China Read the rest of this article »

Posted in 03-2010 (March 2010), Original Research, Photodynamic Therapy | No Comments »

Questions • Challenges • Controversies: How Clinically Relevant is Dapsone-related Peripheral Neuropathy? An Overview of Available Data with Emphasis on Clinical Recognition

March 2010

Morgan McCarty (MS4);
James Q. Del Rosso, DO, FAOCD

Section Editor: James Q. Del Rosso, DO, FAOCD

Ms. McCarty (MS4) is from Midwestern University AZCOM, Glendale, Arizona. Dr. Del Rosso is Dermatology Residency Director, Valley Hospital Medical Center, Las Vegas, Nevada. Disclosure: Ms. McCarty and Dr. Del Rosso report no relevant conflicts of interest. Read the rest of this article »

Posted in 03-2010 (March 2010), Dapsone-related Peripheral Neuropathy, Questions-Challenges-Controversies | 1 Comment »