Questions • Challenges • Controversies: How Clinically Relevant is Dapsone-related Peripheral Neuropathy? An Overview of Available Data with Emphasis on Clinical Recognition
March 2010
Morgan McCarty (MS4);
James Q. Del Rosso, DO, FAOCD
Section Editor: James Q. Del Rosso, DO, FAOCD
Ms. McCarty (MS4) is from Midwestern University AZCOM, Glendale, Arizona. Dr. Del Rosso is Dermatology Residency Director, Valley Hospital Medical Center, Las Vegas, Nevada. Disclosure: Ms. McCarty and Dr. Del Rosso report no relevant conflicts of interest. Read the rest of this article »
Posted in 03-2010 (March 2010), Dapsone-related Peripheral Neuropathy, Questions-Challenges-Controversies | No Comments »
How Much Do We Really Know About Our Favorite Cosmeceutical Ingredients?
February 2010
Jacquelyn Levin, DO; James Q. Del Rosso, DO, FAOCD; Saira B. Momin, DO
Dr. Levin is from the Mohave Skin & Cancer Clinics, Dermatology Research Center, Las Vegas, Nevada; Dr. Del Rosso is Dermatology Residency Director, Valley Hospital Medical Center, Las Vegas, Nevada; Dr. Momin is Chief Dermatology Resident (PGY-4), Valley Hospital Medical Center, Las Vegas, Nevada. Read the rest of this article »
Posted in 02-2010 (February 2010), Cosmeceuticals, Questions-Challenges-Controversies | No Comments »
Seborrheic Dermatitis and Malassezia species: How Are They Related?
November 2009
James Q. Del Rosso, DO, FAOCD; Grace K. Kim, DO
Introduction
Seborrheic dermatitis (SD) is a common inflammatory dermatoses that may affect infants, adolescents, and adults of all ethnicities and races.[1,2] SD exhibits two incidence peaks, one during infancy, and the other during the fourth to sixth decades of life.[3] The prevalence of SD ranges from 1 to 5 percent in the immunocompetent population and increases in the immunocompromised population, especially among patients with acquired immunodeficiency syndrome (AIDS).[2–4] Infantile SD occurs between the second and tenth week of life and peaks at three months of age.[4] Infantile SD is distinguished from adult or adolescent SD in that the infantile form is almost always confined to the first 3 to 12 months of life, while adult SD is characteristically chronic and relapsing throughout life.[5] SD can also present in association with other skin disorders, such as atopic dermatitis (AD), which can often create diagnostic confusion. In one study, 49 percent of children with AD between the ages of 2 to 12 months had a history of infantile SD as compared to 17 percent of controls.[4] SD has also been observed in conjunction with other skin diseases, such as rosacea (rosacea-seborrheic dermatitis overlap), blepharitis, acne vulgaris (AV), pityriasis versicolor, and Malassezia folliculitis.[6–9] Read the rest of this article »
Posted in 11-2009 (November 2009), Malassezia species, Questions-Challenges-Controversies, Seborrheic Dermatitis | No Comments »
Use of Oral Doxycycline for Community-acquired Methicillin-resistant Staphylococcus aureus (CA-MRSA) Infections
April 2009
James Q. Del Rosso, DO, FAOCD;
Sanjay Bhambri, DO;
Grace Kim, DO
Dr. Del Rosso is Dermatology Residency Director, Valley Hospital Medical Center, Las Vegas, Nevada, Touro University College of Osteopathic Medicine, Henderson, Nevada; Clinical Associate Professor, Dermatology, University of Nevada School of Medicine, Las Vegas, Nevada; Las Vegas Skin & Cancer Clinics, Las Vegas and Henderson, Nevada. Dr. Bhambri is Chief Dermatology Resident, Valley Hospital Medical Center, Las Vegas, Nevada. Dr. Kim is a dermatologist at Valley Hospital Medical Center, Las Vegas, Nevada. The authors report no conflicts of interest in relationship to the content of this article. Read the rest of this article »
Posted in 04-2009 (April 2009), Doxycycline Therapy, Questions-Challenges-Controversies | No Comments »
Review of Intravenous Immunoglobulin in the Treatment of Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis
February 2009
by Saira B. Momin, DO
James Q. Del Rosso, DO, FAOCD
Abstract
Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are rare and serious cutaneous adverse reactions. There is controversy over the use of intravenous immunoglobulin (IVIG) in the treatment of SJS or TEN. The lack of randomized controlled trials to assess the benefits and risks of IVIG is due to its low prevalence and the high mortality rate associated with these cutaneous adverse reactions, especially in TEN. This article reviews published literature on case series that either supports or refutes the use of IVIG in the treatment of SJS or TEN. Read the rest of this article »
Posted in 02-2009 (February 2009), Questions-Challenges-Controversies | No Comments »
Weight-based Dosing and Extended-release Formulation of Minocycline Tablets — Is There Clinical Significance?
January 2009
by James Q. Del Rosso, DO, FAOCD
Dr. James Del Rosso, DO, FAOCD, is Dermatology Residency Director, Valley Hospital Medical Center; Clinical Associate Professor (Dermatology), University of Nevada School of Medicine, Las Vegas, Nevada; and Associate Professor (Dermatology), Touro University College of Osteopathic Medicine, Henderson, Nevada.
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Posted in 01-2009 (January 2009), Acne, Questions-Challenges-Controversies | No Comments »
What is the Role of Benzoyl Peroxide Cleansers in Acne Management? Do they Decrease Propionibacterium acnes Counts? Do they Reduce Acne Lesions?
November 2008
by James Q. Del Rosso, DO, FAOCD
Dr. James Del Rosso, DO, FAOCD, is Dermatology Residency Director, Valley Hospital Medical Center; Clinical Associate Professor (Dermatology), University of Nevada School of Medicine, Las Vegas, Nevada; and Associate Professor (Dermatology), Touro University College of Osteopathic Medicine, Henderson, Nevada.
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Posted in 11-2008 (November 2008), Acne, General, Questions-Challenges-Controversies | No Comments »
Topical Imiquimod Therapy for Actinic Keratosis Is Long-Term Clearance a Realistic Benefit?
September 2008
by James Q. Del Rosso, DO, FAOCD
Dr. James Del Rosso, DO, FAOCD, is Dermatology Residency Director, Valley Hospital Medical Center; Clinical Associate Professor (Dermatology), University of Nevada School of Medicine, Las Vegas, Nevada; and Associate Professor (Dermatology), Touro University College of Osteopathic Medicine, Henderson, Nevada.
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Posted in 09-2008 (September 2008), Actinic Keratosis, Questions-Challenges-Controversies | No Comments »
