Steven M. Dean, DO, FACP, RPVI; Matthew Zirwas, MD
The Ohio State University, Columbus, Ohio

Disclosure: Drs. Dean and Zirwas report no relevant conflicts of interest.

Abstract
Pyoderma gangrenosum is a painful, noninfectious, ulcerative, cutaneous disorder that most commonly affects the lower extremities. The diagnosis is made by recognizing the characteristic clinical manifestations in the setting of a causative systemic disease and excluding other causes of similar-appearing ulcerations. Pyoderma gangrenosum often evolves in the setting of systemic illnesses, such as inflammatory bowel disease, rheumatological disorders, and hematological conditions. However, several medications have rarely been linked to pyoderma gangrenosum. The authors report the second case of sunitinib-associated pyoderma gangrenosum in a 61-year-old patient with recurrent renal cell carcinoma.  (J Clin Aesthetic Dermatol. 2010;3(8):34–35.) Read the rest of this article »

by Elissa M. Schwartzfarb, BS, Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, Florida;

Dot Weir, RN, CWON, CWS, Clinical Director, The Wound Center at Osceola Regional Medical Center, Kissimee, Florida;

Walter A. Conlan III, MD, CWS, Medical Director, The Wound Center at Osceola Regional Medical Center, Kissimee, Florida;

Paolo Romanelli, MD, Associate Clinical Professor, Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, Florida;

Robert S. Kirsner, MD, PhD, Vice-Chairman and The Stiefel Laboratories Professor of Medical Dermatology, Department of Dermatology and Cutaneous Surgery, Department of Epidemiology and Public Health, University of Miami Miller School of Medicine, Miami, Florida Read the rest of this article »