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A Review of the Safety and Efficacy of Benzoyl Peroxide (5.3%) Emollient Foam in the Management of Truncal Acne Vulgaris

November 2010

Joseph Bikowski, MD
Clinical Assistant Professor, Department of Dermatology, Ohio State University, Columbus, Ohio; Bikowski Skin Care Center at Sewickley Station, Sewickley, Pennsylvania

Dr. Bikowski discloses the following: Allergan—speakers’ bureau, honoraria; Coria—advisory board, consultant, honoraria, speakers’ bureau; Galderma—advisory board, consultant, honoraria, speakers’ bureau; OrthoNeutrogena—advisory board, consultant, honoraria, speakers’ bureau; Stiefel, a GSK Company—advisory board, consultant, honoraria, speakers’ bureau. Read the rest of this article »

Posted in 11-2010 (November 2010), Acne, Benzoyl Peroxide, Literature Review | No Comments »

A Meta-analysis to Investigate the Relation Between Fitzpatrick Skin Types and Tolerability of Adapalene-Benzoyl Peroxide Topical Gel in Subjects with Mild or Moderate Acne

August 2010

Valerie D. Callender, MD is from Callender Skin and Laser Center, Mitchellville, Maryland. Norman Preston, PhD; Cris Osborn, PhD; Lori Johnson, PhD; and Ronald W. Gottschalk, MD are from Galderma Laboratories, LP, Fort Worth, Texas

Disclosure: Dr. Callender is a clinical researcher and consultant for Galderma. Drs. Preston, Osborn, Johnson, and Gottschalk are employed by Galderma. Read the rest of this article »

Posted in 08-2010 (August 2010), Acne, Adapalene-Benzoyl Peroxide, Meta-Analysis | No Comments »

Three-dimensional, Full-sized, Silicone-based, Facial Replicas for Teaching Outcome Measures in Acne

June 2010

Jerry K. L. Tan, MD, FRCPC; Jing Tang, MSc

Dr. Tan is Adjunct Professor, University of Western Ontario and Windsor Clinical Research Inc., Windsor, Ontario, Canada. Jing Tang is Statistician, Windsor Clinical Research Inc., Windsor, Ontario, Canada (currently with Fraser Health Authority, Vancouver, British Columbia, Canada) Read the rest of this article »

Posted in 06-2010 (June 2010), Acne, Original Research | No Comments »

A Review of Acne in Ethnic Skin: Pathogenesis, Clinical Manifestations, and Management Strategies

April 2010

Erica C. Davis, MD; Valerie D. Callender, MD

Dr. Davis is from Callender Skin & Laser Center, Mitchellville, Maryland.
Dr. Callendar is from Callender Skin & Laser Center, Mitchellville, Maryland and Department of Dermatology, Howard University College of Medicine, Washington, DC. Read the rest of this article »

Posted in 04-2010 (April 2010), Acne, Literature Review | No Comments »

A Three-Step Acne System Containing Solubilized Benzoyl Peroxide versus Benzoyl Peroxide/Clindamycin in Pediatric Patients with Acne

November 2009

Lawrence F. Eichenfield, MD, Rady Children’s Hospital, San Diego, and University of California San Diego, San Diego, California; Diane Thiboutot, MD, Penn State University College of Medicine, Hershey, Pennsylvania; Alan Shalita, MD, SUNY Downstate Medical Center, Brooklyn, New York; Leonard Swinyer, MD, Dermatology Research Center, Salt Lake City, Utah; Emil Tanghetti, MD, Center for Dermatology and Laser Surgery, Sacramento, California; Eduardo Tschen, MD, Academic Dermatology Associates, Albuquerque, New Mexico; Lisa Parr, PharmD, Clinical Affairs Department, OMP, Inc., Long Beach, California Read the rest of this article »

Posted in 11-2009 (November 2009), Acne, Original Research | No Comments »

The Use of Sodium Sulfacetamide 10%-Sulfur 5% Emollient Foam in the Treatment of Acne Vulgaris

August 2009

James Q. Del Rosso, DO, FAOCD, Valley Hospital Medical Center, Las Vegas, Nevada

Abstract
Acne vulgaris is the most common disorder encountered in ambulatory clinical practice comprising 11.3 percent of office visits to dermatologists in 2005.[1] By comparison, eczematous dermatoses, psoriasis, and skin cancer accounted for 6.2, 3.5, and 10 percent of office visits, respectively.[1] A variety of topical therapeutic options are available for treatment of acne vulgaris, including benzoyl peroxide, antibiotics, retinoids, azelaic acid, and sodium sulfacetamide-sulfur.[2,3] Sodium sulfacetamide 10%-sulfur 5% has been used for the topical treatment of seborrheic dermatitis, acne vulgaris, and rosacea since the mid-1950s and is available in a variety of formulations, including lotions, creams, cleansers, and emollient foams.[4] Recently, an emollient foam sodium sulfacetamide 10%-sulfur 5% formulation indicated for topical therapy of acne vulgaris, rosacea, and seborrheic dermatitis has become available.[5] This article provides an overview of the sodium sulfacetamide 10%-sulfur 5% emollient foam and reports the results of a case report series of patients with acne vulgaris treated with sodium sulfacetamide 10%-sulfur 5% emollient foam as monotherapy or in combination with other topical acne products.

(J Clin Aesthetic Dermatol. 2009;2(8):26–29.) Read the rest of this article »

Posted in 08-2009 (August 2009), Acne, Case Series | No Comments »

A 6% Benzoyl Peroxide Foaming Cloth Cleanser Used in the Treatment of Acne Vulgaris: Aesthetic Characteristics, Patient Preference Considerations, and Impact on Compliance with Treatment

July 2009

James Q. Del Rosso, DO, FAOCD
Valley Hospital Medical Center, Las Vegas, Nevada

Abstract
Objective: The study was conducted to evaluate the product attributes of a new benzoyl peroxide-containing foaming cloth cleanser and to compare the overall patient satisfaction of this product with two currently available benzoyl peroxide acne products (6% benzoyl peroxide cleanser and 4% benzoyl peroxide wash). Design: This was a randomized, single-blind study. Setting: Two clinical trial sites. Participants: Male and female subjects (N=193) aged 17 to 30 years with a history of acne vulgaris were enrolled. Measures: Subjects initially cleansed their face with the benzoyl peroxide foaming cloth and then completed a product-attribute survey. Following an interval of five minutes or more, subjects cleansed their face again using one of two randomly assigned comparator benzoyl peroxide-containing cleansing products and then completed a comparative survey. Survey results were tabulated and a top-two box analysis was performed. Results: Following the use of the benzoyl peroxide-containing foaming cloth, 94 percent of the product-attribute responses were positive (p?0.05). With respect to convenience, usability, and cosmetic elegance, the majority of subjects indicated a preference for the benzoyl peroxide foaming cloth compared to the 6% benzoyl peroxide cleanser and 4% benzoyl peroxide wash (for each, p?0.05). There were no reports of adverse events. Conclusion: These attributes supporting preference for the benzoyl peroxide foaming cloth cleanser may improve patient satisfaction with topical acne treatment resulting in improved patient compliance.  (J Clin Aesthetic Dermatol. 2009;2(7):26–29.) Read the rest of this article »

Posted in 07-2009 (July 2009), Acne, Original Research | No Comments »

A New, Once-daily, Optimized, Fixed Combination of Clindamycin Phosphate 1.2% and Low-concentration Benzoyl Peroxide 2.5% Gel for the Treatment of Moderate-to-Severe Acne

May 2009

Michael H. Gold, MD
Gold Skin Care Center and Tennessee Clinical Research Center, Nashville, Tennessee Read the rest of this article »

Posted in 05-2009 (May 2009), Acne, Areas of Interest, Literature Review | No Comments »

Clinical Efficacy of Self-applied Blue Light Therapy for Mild-to-Moderate Facial Acne

March 2009

Michael H. Gold, MD; Tennessee Clinical Research Center, Nashville, Tennessee; Anneke Andriessen; RBC Consultants, The Netherlands; Julie Biron; Tennessee Clinical Research Center, Nashville, Tennessee; Hinke Andriessen; RBC Consultants, The Netherlands Read the rest of this article »

Posted in 03-2009 (March 2009), Acne, General, Original Research | No Comments »

Weight-based Dosing and Extended-release Formulation of Minocycline Tablets — Is There Clinical Significance?

January 2009

by James Q. Del Rosso, DO, FAOCD

Dr. James Del Rosso, DO, FAOCD, is Dermatology Residency Director, Valley Hospital Medical Center; Clinical Associate Professor (Dermatology), University of Nevada School of Medicine, Las Vegas, Nevada; and Associate Professor (Dermatology), Touro University College of Osteopathic Medicine, Henderson, Nevada.

Read the rest of this article »

Posted in 01-2009 (January 2009), Acne, Questions-Challenges-Controversies | No Comments »