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Clinical Pearl: Comedone Extraction for Persistent Macrocomedones While on Isotretinoin Therapy

November 2011

Physical Modalities for Acne, Rosacea, and their Sequelae
Section Editor: Emmy M. Graber, MD

This month’s installment by Emily M. Wise, MD; Emmy M. Graber, MD

Dr. Graber is Assistant Professor, Department of Dermatology, Boston University, Boston, Massachusetts. Dr. Wise is Resident in Dermatology, Boston University School of Medicine, Department of Dermatology, Boston, Massachusetts. Disclosure: Drs. Graber and Wise report no relevant conflicts of interest.

Abstract
In the past, the safety of performing procedures while patients are on isotretinoin has been questioned. Macrocomedones are traditionally resistant to treatment with isotretinoin alone. The authors present a technique that is safe to employ while patients are on isotretinoin to effectively eliminate macrocomedones without complication. Read the rest of this article »

Posted in 11-2011 (November 2011), Physical Modalities for Acne Rosacea and their Sequelae | No Comments »

Tretinoin: A Review of Its Anti-inflammatory Properties in the Treatment of Acne

November 2011

Nicholas Schmidt, PhD; Eugene H. Gans, PhD

Drs. Schmidt and Gans are from Medicis Pharmaceutical Corporation, Scottsdale, Arizona

Disclosure: The preparation of this manuscript was funded by Medicis Pharmaceutical Corporation, Scottsdale, Arizona. Drs. Schmidt and Gans are consultants for Medicis Pharmaceutical Corporation and have no financial interest. Read the rest of this article »

Posted in 11-2011 (November 2011), Literature Review | No Comments »

Synergy and Its Clinical Relevance in Topical Acne Therapy

November 2011

by Leon H. Kircik, MD

Dr. Kircik is from Indiana University School of Medicine, Indianapolis, Indiana; Mount Sinai Medical Center, New York, New York; DermResearch, PLLC, Louisville, Kentucky

Disclosure: Dr. Kircik is a consultant, speaker, investigator, and advisory board member for Galderma. Read the rest of this article »

Posted in 11-2011 (November 2011), Literature Review | No Comments »

Randomized Controlled Trial of Desonide Hydrogel 0.05% versus Desonide Ointment 0.05% in the Treatment of Mild-to-moderate Atopic Dermatitis

November 2011

Nathan S. Trookman, MD, FAAD; Ronald L. Rizer, PhD

Dr. Trookman is from Colorado Springs Dermatology Clinic, Colorado Springs, Colorado, and Dr. Rizer is from Thomas J. Stephens & Associates, Inc., Colorado Research Center, Colorado Springs, Colorado

Disclosure: The authors report no relevant conflicts of interest. Financial support for this study was provided by SkinMedica, Inc. Read the rest of this article »

Posted in 11-2011 (November 2011), Original Research | No Comments »

Frequency of Contact Allergens in Pediatric Patients with Atopic Dermatitis

November 2011

by Elise M. Herro, MD; Catalina Matiz, MD; Kim Sullivan; Curt Hamann, MD; Sharon E. Jacob, MD

Drs. Herro, Matiz, and Jacob are from the Division of Pediatric and Adolescent Dermatology, Rady Children’s Hospital, University of California, San Diego; Dr. Hamann is from SmartPractice USA, Phoenix, Arizona

Disclosure: The authors’ center performed the SmartPractice USA-sponsored Pediatric Research Equity Act (PREA) TRUE Test® 1.1, 2.1, and 3.1 safety and efficacy trial in children and adolescents. The authors have no other financial disclosures to declare related to the content of this article. No funding was received in conjunction with this retrospective study. Read the rest of this article »

Posted in 11-2011 (November 2011), Original Research | No Comments »

Treatment of Widespread Granuloma Annulare with Adalimumab: A Case Report

November 2011

by Heidi Kozic, MD; Guy F. Webster, MD, PhD

Dr. Kozic is from Panzer Dermatology, Newark, Delaware, and Dr. Webster is from Jefferson Medical College, Department of Dermatology, Philadelphia, Pennsylvania

Disclosure: Dr. Kozic reports no relevant conflicts of interest. Dr. Webster is a consultant for Abbott.

Abstract
The authors report a case of widespread granuloma annulare that was resistant to multiple systemic therapies, but responded rapidly to a short course of adalimumab.  (J Clin Aesthet Dermatol. 2011;4(11):42–43.) Read the rest of this article »

Posted in 11-2011 (November 2011), Case Report | No Comments »

Paederus Dermatitis: An Outbreak on a Medical Mission Boat in the Amazon

November 2011

by Jere J. Mammino, DO, FAOCD
Advanced Dermatology, Oviedo, Florida

Disclosure: The author reports no relevant conflicts of interest.

Abstract
Paederus dermatitis is a peculiar, irritant contact dermatitis characterized by a sudden onset of erythematobullous lesions on exposed areas of the body. The disease is provoked by an insect belonging to the genus Paederus. This beetle does not bite or sting, but accidental brushing against or crushing the beetle over the skin provokes the release of its coelomic fluid, which contains paederin, a potent vesicant agent. This article describes this dermatitis, which occurred in three healthcare personnel aboard a medical mission boat on the Amazon River. The epidemiology and pathogenesis of paederus dermatitis is reviewed as well its treatment and prevention.
(J Clin Aesthet Dermatol. 2011;4(11):44–46.) Read the rest of this article »

Posted in 11-2011 (November 2011), Case Report | No Comments »